For the first time since the league's inception in 1956, the Eredivisie will end the season without a champion in 2020.
Ajax have been denied the 2019-20 title after the decision was made to end the season with immediate effect due to the coronavirus pandemic.
Following consultation between clubs and The Royal Dutch Football Association (KNVB), there will be no promotion to or relegation from Holland's top flight.
Reigning Eredivisie champions Ajax, who were ahead of rivals AZ Alkmaar on goal difference with nine league matches remaining, have been denied their 35th league title as a result.
"Unfortunately, with the cabinet's most recent corona measures, it has become impossible to complete the 2019/2020 season of professional football competitions in time - it will be crystal clear to everyone involved, from supporters and players to directors and referees, that public health always comes first," a KNVB statement read.
"The professional football board, after consulting clubs, players and coaches, and with the approval of the Supervisory Board, has decided to stop the 2019/20 competition and to allow the allocation of European club football seats based on the current league table.
"This is in accordance with UEFA guidelines. In relation to promotion and demotion, it has been decided not to promote and not to be demoted."
Ajax abstained from the vote, while AZ have announced that they are considering their options following the decision.
Pending UEFA ratification, Ajax will now go directly to the play-offs of next season's Champions League, with AZ set to compete in the second qualifying round.
Feeyenord, who finished third, will progress straight to the group stages of the Europa League. PSV and Willem II will enter the qualifyiers.
Despite Ajax leading on goal difference, AZ did a league double over Erik ten Hag's team.
Reacting to the news, Ajax CEO Edwin van der Sar said there were more important things than football.
"As a player and as a club you naturally want to become champion," he said.
"You want to show it on the field and we have been at the top all year round. Then it is a pity that you are not declared champion, but in this situation that may be understandable. There are more important things at the moment than football."
Ajax captain Dusan Tadic and winger Hakim Ziyech - who is set for a summer switch to Chelsea - have both criticized the decision.
"It is what you agree on. The goal difference would count in a tie," former Southampton playmaker Tadic said.
"If you had agreed that the head-to-head result would count then AZ would have been the champion for me. I am a pro and want to win every trophy. That's what I do it for. Now I have lost a prize, that's how it feels."
Ziyech also slammed the decision not to award Ajax the title.
"Come on, what nonsense I have heard. We are at the top anyway," he told AD.
All those stories that AZ deserved more because they won twice against us. So the goal difference, as it always is, doesn't count now? Bullshit, of course. How did PSV become champion in 2007? Exactly, on one goal."
The Eredivisie Women, led by PSV, has also been cancelled without naming a champion.
PSV will enter the group stages of the Champions League as compensation, with second-placed Ajax entering the qualifiers.